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Posted by cynthia urbyte
In Reply to: Anticonvulsants and Tinnitus (ringing in ears) posted by Mike
Hello Mike,
I have severe migraines on a daily basis. I have taken both Depakote and Topomax
but the side effects from both were worse that the migraines and now I'm back to
square one again.
I had tinnitus with Depakote and with Topomax. Stopped Depakote due to 10 lb
weight gain. (I am petite and can't afford gaining). I was taking Topomax for
almost a yr. but stopped because of 10 - 15 lb. weight loss, severe drying of
the mouth and being constantly thirsty. I had kidney stones as well which is a
nasty side effect of Topomax.
Well, I hope this information helps.
cynthia
==============================================
"Mike [remove (SPAM_BLOCKER) from my email address to reply]" wrote:
> Please excuse the crossposts, but I need advice form all fronts.
>
> I have been recently given Depakote (1g/ day extended release Divalproex
> Sodium) tablet for Migraine prevention. I am also weaning off of a low-dose
> of Klonipin that I was on for 3 months (1mg/day). The Depakote was supposed
> to help with the weaning process (I'm not so sure about that). I have
> tolerated the depakote pretty well, except that it has made my ears ring
> significantly more than usual (I have preexisting tinnitus, which is
> supposedly being caused by these almost constant migraines, the Klonipin
> helped the ringing, so this is a bit complex), although it may be from the
> Klonipin withdrawal or maybe an interaction between the two--I noticed the
> negative effect on my hearing right away). I am obviously concerned about
> this development because the ringing has bvecome more like sirens and
> wondered if anyione else had this experience. According to the FDA,
> Depakote can cause or aggravate tinnitus in 1-7% of users, but that number
> seems to be the same for other anticonvulsants as well.
>
> Some of the other options (if my doctor lets me) are Nerontin(Gabapentin)
> and Topramax(Topiramate). I have read that Topramax is being studied for
> tinnitus, but all of the others (including Depakote) have shown promise in
> some people as well. I wondered what your experiences were on these
> medicines. Also, how effective are they for Migraines? My migraine doc is
> absolutely in love with Depakote. When I complained to him about it, he
> told me to persevere. Not what I wanted to hear! I didn't want to push too
> hard, since he is an expert on my very strange form of migraine and was the
> first neurologist to identify the problem and offer any meaningful help.
